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  • Title: Role of 18F-fluorodeoxyglucose PET in the study of neuroendocrine tumors.
    Author: Panagiotidis E, Bomanji J.
    Journal: PET Clin; 2014 Jan; 9(1):43-55. PubMed ID: 25029933.
    Abstract:
    The most widely used PET radiopharmaceutical in daily clinical practice is (18)F-fluorodeoxyglucose (FDG). The evaluation of glycolytic metabolism by (18)F-FDG is potentially useful in identifying high-risk patients with aggressive neuroendocrine disease associated with a poor outcome. Although the use of new somatostatin analogues labeled with 68-Gallium for PET has significantly increased the sensitivity of NET imaging compared with single photon emission computed tomography and (18)F-FDG-PET, (18)F-FDG may retain an important role in managing patients with NETs owing to its high prognostic value and its higher sensitivity in delineating disease extent, especially in aggressive and high-grade tumors.
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