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  • Title: Thrombolysis of occluded femoropopliteal graft with locally delivered human plasmin.
    Author: Nenezić D, Radak D, Gajin P, Tanasković S, Novaković A, Matić P.
    Journal: Srp Arh Celok Lek; 2014; 142(5-6):342-6. PubMed ID: 25033592.
    Abstract:
    INTRODUCTION: Acute lower limb ischemia results from thrombosis or embolization of diseased native artery or previously implanted bypass graft. When this occurs, several options are available to restore blood flow: catheter-directed thrombolysis, mechanical thrombectomy or open surgery. Fundamental reasons to apply percutaneous interventions are avoiding open procedures in high risk patients, and avoiding difficult dissection through scar tissue. CASE OUTLINE: A 67-year-old male was admitted at our Institution for critical limb ischemia. After performed angiography the diagnosis of occluded femoropopliteal graft was established. Occlusion was resolved by catheter-directed thrombolysis with plasmin. Culprit lesions were treated by angioplasty. CONCLUSION: Our patient underwent a successful thrombolysis of occluded femoropopliteal graft with locally-delivered human plasmin.
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