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  • Title: [von Recklinghausen's disease associated with malignant lymphoma].
    Author: Matsuzaki M, Shimamoto Y, Yokoyama Y, Suga K, Tokioka T, Sueoka E, Ono K, Sano M, Yamaguchi M.
    Journal: Rinsho Ketsueki; 1989 Mar; 30(3):382-6. PubMed ID: 2504974.
    Abstract:
    A 59-year-old man was admitted to the Saga Medical School Hospital in November 1986 because of unconsciousness and lymph node swelling. He had café au leit spots and multiple neurofibromas since his thirties. The leukocyte count was increased. The level of serum LDH and Ca were extremely elevated. His bone marrow aspiration showed the invasion of lymphoma cells. Lymph node biopsy from his left neck and the study of surface markers were performed. And then, his illness was diagnosed as non-Hodgkin's lymphoma (diffuse, medium sized cell type, B cell type, stage IV B.) following von Recklinghausen's disease. After the admission, his general condition improved by chemotherapy, but he had a relapse 6 months later. And he died in November 1987. The case of von Recklinghausen's disease associated with malignant lymphoma in rarely reported. We reviewed the literature and discussed von Recklinghausen's disease associated with malignant lymphoma including this case.
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