These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Silver(I)(pyridine-containing ligand)] complexes as unusual catalysts for A(3)-coupling reactions.
    Author: Trose M, Dell'Acqua M, Pedrazzini T, Pirovano V, Gallo E, Rossi E, Caselli A, Abbiati G.
    Journal: J Org Chem; 2014 Aug 15; 79(16):7311-20. PubMed ID: 25051223.
    Abstract:
    Two original macrocyclic silver(I)(pyridine-containing ligand) complexes [Ag(I)(Pc-L)] were synthesized and characterized. Their ability to catalyze the coupling among aldehydes, terminal alkynes and amines (A(3)-coupling) was demonstrated. The reaction could be performed under conventional as well as dielectric heating. The catalysts were effective in both cases, but dielectric heating allowed a lower catalyst loading and reduced ratio among reaction partners in shorter reaction times. The reaction scope was broad, including aryl/alkyl aldehydes, aryl/alkyl acetylenes and secondary aliphatic amines. Some unprecedented propargylamines have been prepared. The new catalytic system was also tested with more challenging coupling partners such as aniline and ketones.
    [Abstract] [Full Text] [Related] [New Search]