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  • Title: [Contribution of perindopril to the treatment of chronic congestive cardiac insufficiency. Multicenter pilot double blind study versus placebo].
    Author: Bounhoure JP, Bottineau G, Lechat P, Garnham J, Lapeyre G.
    Journal: Arch Mal Coeur Vaiss; 1989 May; 82 Spec No 1():73-8. PubMed ID: 2505716.
    Abstract:
    Cardiac decompensation occurred in three patients of the placebo group, but not in the perindopril group. The effectiveness of perindopril in heart failure was demonstrated by the improvement observed in exercise test and severity score and by the decrease of cardiothoracic ratio. Changes in SAP, and serum creatinine levels, in particular, showed that the drug was well tolerated.
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