These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Antibodies against the major core protein p24 of human immunodeficiency virus: relation to immunological, clinical and prognostic findings.
    Author: Lindhardt BO, Gerstoft J, Hofmann B, Pallesen G, Mathiesen L, Dickmeiss E, Ulrich K.
    Journal: Eur J Clin Microbiol Infect Dis; 1989 Jul; 8(7):614-9. PubMed ID: 2506021.
    Abstract:
    In 79 homosexual men positive for antibody to human immunodeficiency virus (HIV), the titer and avidity of p24 antibody was determined by an indirect ELISA and the serum tested for the presence of HIV antigen. Results were examined for a possible correlation with clinical, immunological and prognostic findings. High titers and low avidity of p24 antibodies correlated significantly with a normal pokeweed mitogen response, early lymph node changes, and an asymptomatic and stable clinical condition. In HIV antigen negative patients, low titers and high avidity of p24 antibodies correlated significantly with a progressive clinical condition. The finding of primarily high avidity antibodies against p24 antigen in patients with more advanced immunodeficiency indicates that a decline of p24 antibodies during the clinical course of HIV infection may not be explained exclusively by an increased production of viral proteins.
    [Abstract] [Full Text] [Related] [New Search]