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  • Title: Anti-asialo-GM1 and GD1a variant of Miller Fisher variant of Guillain-Barré Syndrome.
    Author: Morgan ML, Law N, Espino Barros Palau A, Saeed U, Yalmanchili S, Lee AG.
    Journal: J Neuroophthalmol; 2014 Dec; 34(4):377-9. PubMed ID: 25062498.
    Abstract:
    We present a woman with acute onset of bilateral ophthalmoparesis and ataxia occurring 4 weeks after gastroenteritis. Serum antibody titers against asialo-GM1 and GD1a, typically associated with inflammatory axonal neuropathies, were elevated but titers against anti-GQ1b, the most commonly found antibody found in the Miller Fisher variant of Guillain-Barre syndrome were not. No other etiology for ophthalmoparesis was found despite extensive patient evaluation. Intravenous immunoglobulin was administered, and the patient gradually improved over subsequent months. This case is unique for its antiganglioside antibody profile associated with Miller Fisher syndrome.
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