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  • Title: Highly sensitive methyltransferase activity assay and inhibitor screening based on fluorescence quenching of graphene oxide integrated with the site-specific cleavage of restriction endonuclease.
    Author: Ji L, Cai Z, Qian Y, Wu P, Zhang H, Cai C.
    Journal: Chem Commun (Camb); 2014 Sep 21; 50(73):10691-4. PubMed ID: 25077742.
    Abstract:
    We report a sensitive and selective approach for the DNA methyltransferase (MTase) activity assay and MTase inhibitor screening by coupling the fluorescence quenching of graphene oxide with site-specific cleavage of a restriction endonuclease.
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