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  • Title: Postnatal development of pancreatic alpha-amylase and intestinal saccharase and lactase in rat sucklings as related to thyroid function of mothers.
    Author: Turakulov JC, Rakhimov KR, Karimova SF, Kuchkarova LS.
    Journal: Endocrinol Exp; 1989 Sep; 23(3):217-27. PubMed ID: 2509196.
    Abstract:
    The treatment of lactating mothers with 50 micrograms/100 g b.w. thyroxine s.c. daily from the 1st to 21st day of lactation resulted in earlier induction of alpha-glucosidases (pancreatic alpha-amylase, intestinal saccharase) and in earlier repression of beta-galactosidases (intestinal lactase). In contrast, the sucklings fed by thyroidectomized mothers showed a delayed induction of pancreatic alpha-amylolytic activity and intestinal saccharase, but ameliorated the repression of lactase. The treatment of another group of thyroidectomized mothers with 5 micrograms/100 g b.w. thyroxine prevented such effects mothers of thyroidectomy in sucklings.
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