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  • Title: Safe use of thrombolysis in the elderly.
    Author: Wittry MD, Thornton TA, Chaitman BR.
    Journal: Geriatrics; 1989 Nov; 44(11):28-30, 33-6. PubMed ID: 2509296.
    Abstract:
    Elderly individuals with acute myocardial infarction represent a high-risk population that may benefit the most from thrombolytic therapy. To date, studies with streptokinase, tissue plasminogen activator (t-PA), and APSAC have shown improved survival in patients up to age 80, although there was an increased risk for hemorrhagic complications. While a placebo-controlled trial is needed to confirm these findings in even older patients, careful screening of the individual should make thrombolysis safe and effective for selected patients in this age group.
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