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Title: [Monitoring options and reversal agents for oral anticoagulants]. Author: Thorup SB, Husted SE, Vang ML. Journal: Ugeskr Laeger; 2014 Apr 28; 176(9):. PubMed ID: 25096568. Abstract: The approval of the oral direct thrombin inhibitor dabigatranetexilat and the oral factor Xa inhibitors rivaroxaban and apixaban as thromboprophylaxis challenges the position of the vitamin K antagonists (VKA). Predictable pharmacodynamics gives the new oral anticoagulants an advantageous profile. Unlike VKAs there is no specific reversal agent available for the new oral anticoagulants. Experience with haemostatic products for the emergency management of critical bleeding caused by these agents is limited.[Abstract] [Full Text] [Related] [New Search]