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  • Title: [The effect of physical stress on the blood flow velocity in the middle cerebral artery. A transcranial Doppler sonographic study].
    Author: Briebach T, Laubenberger J, Fischer PA.
    Journal: Ultraschall Med; 1989 Oct; 10(5):250-3. PubMed ID: 2510295.
    Abstract:
    Changes in blood flow velocity of the middle cerebral artery (MCA) were measured by transcranial Doppler Sonography in 10 healthy subjects during a 10-minute period of moderate bicycle exercise. During physical exercise, a marked increase in heart rate (+63%) und ventilation rate (+48%) and a moderate increase in mean arterial blood pressure (+16%) were found. The end tidal carbon dioxide partial pressure rose in all cases by a mean value of 6.7 mmHg. The MCA flow velocity increased from 62 cm/s to 75 cm/s by 13 cm/s or 21% (mean values). When corrected to a standard pCO2 of 40 mmHg no significant changes in flow velocities (-1 cm/s) were found. Our Doppler sonographic findings indicate that during moderate physical exercises the MCA flow velocity - and the cerebral circulation - are regulated by the carbon dioxide partial pressure and not by cardiac output.
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