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  • Title: [Arrhythmogenic effect of flecainide--treatment with i.v. magnesium].
    Author: Mletzko R, Jung W, Manz M, Kamradt T, Vogel F, Lüderitz B.
    Journal: Z Kardiol; 1989 Sep; 78(9):602-6. PubMed ID: 2510412.
    Abstract:
    We report on a 46-year-old woman with ventricular tachycardia and ventricular fibrillation after starting antiarrhythmic drug therapy with flecainide. The flecainide acetate plasma levels were always in the normal range. A successful therapeutical intervention was induced with two i.v. applications of 1,000 mg magnesium glutamate. A persistent suppression of ventricular rhythm disturbance was accomplished by continuous i.v. application of 4 mg magnesium glutamate/min.
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