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  • Title: [Canthaxanthin retinopathy and macular pucker--clinical picture and ultrastructural findings of macular pucker].
    Author: Bopp S, el-Hifnawi E, Laqua H.
    Journal: Fortschr Ophthalmol; 1989; 86(5):456-60. PubMed ID: 2511128.
    Abstract:
    Canthaxanthine retinopathy is a crystalline retinopathy that follow oral ingestion of canthaxanthine-containing drugs. We describe the clinical course of a patient with canthaxanthine retinopathy and preexisting idiopathic macular pucker over a period of 2.5 years. Light microscopic investigation of the macular pucker revealed a fibrocellular membrane containing granular, birefringent material and vacuoles within the cells of the membrane resulting from canthaxanthine deposits in the epiretinal membrane. Long-term follow-up shows a slight, but significant, reduction of the retinal crystals.
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