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Title: Interaction between Streptococcus pneumoniae and Branhamella catarrhalis obtained from double-colonized, healthy nasopharynx and double-infected, diseased middle ear cavity. Author: Stenfors LE, Räisänen S. Journal: Scand J Infect Dis; 1989; 21(4):397-401. PubMed ID: 2511622. Abstract: Streptococcus pneumoniae and Branhamella catarrhalis were obtained from the double-colonized nasopharynx of 3 healthy carriers and from the double-infected middle ear cavity of 3 patients suffering from acute otitis media. The bacterial strains were isolated and injected both separately and together into brain-heart infusion broth. Separately injected, both S. pneumoniae and B. catarrhalis survived in the broth for at least 48 h. When injected together, B. catarrhalis was completely suppressed after 16-24 h, whereas S. pneumoniae survived for at least 48 h. Thus S. pneumoniae had a remarkable inhibitory growth effect on B. catarrhalis, which can explain why double-infected middle ear cavities so seldom are found during acute otitis media.[Abstract] [Full Text] [Related] [New Search]