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  • Title: Changes in the arterial to end-tidal PCO2 differences during coronary artery bypass grafting.
    Author: Fletcher R, Veintemilla F.
    Journal: Acta Anaesthesiol Scand; 1989 Nov; 33(8):656-9. PubMed ID: 2511727.
    Abstract:
    The arterial to end-tidal PCO2 difference, PaCO2-PE,CO2, was measured at four different stages during coronary artery bypass grafting in 43 patients: 1) before sternotomy; 2) after sternotomy, sternum retracted; 3) after bypass, sternum still retracted; 4) sternum closed. Mean PaCO2-PE,CO2 initially was 0.6 kPa and changed scarcely at all during the procedure. There were, however, some moderate individual changes in PaCO2-PE,CO2 during surgery, the range of changes compared to the initial value being from -1.4 to +1.3 kPa. The standard deviations for the changes from stage to stage were 0.3-0.4 kPa. PaCO2-PE,CO2 changed by more than 0.5 kPa on only 12 occasions in ten patients. The limitations of PaCO2-PE,CO2 as an index of the alveolar deadspace fraction and the efficiency of ventilation are discussed.
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