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  • Title: Monoclonal antibody direct immunofluorescence for the identification of Neisseria gonorrhoeae strains grown on selective culture media.
    Author: Cavicchini S, Alessi E.
    Journal: Sex Transm Dis; 1989; 16(4):195-7. PubMed ID: 2512657.
    Abstract:
    Commercially available reagents for monoclonal antibody immunofluorescence, polyclonal antibody immunofluorescence, and coagglutination were employed in comparison with a rapid sugar fermentation test used for identifying clinical isolates of Neisseria gonorrhoeae recovered on modified Thayer-Martin media. Of 68 gonococcal strains, 68 were positive by the monoclonal immunofluorescent antibody. Of 16 nongonococcal gram-negative, oxidase-positive diplococci, all were negative by this reagent. Monoclonal antibody immunofluorescence was more specific and more sensitive than polyclonal antibody immunofluorescence and more sensitive than coagglutination.
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