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  • Title: [Lipid peroxidation and the life span of Drosophila melanogaster].
    Author: Muradian KhK, Sabko VE.
    Journal: Zh Evol Biokhim Fiziol; 1989; 25(4):431-5. PubMed ID: 2512751.
    Abstract:
    Studies have been made on the relationship between incubation temperature (20-30 degrees C) of D. melanogaster and the life span as well as the content of various products of lipid peroxidation. It was shown that the increase in the environmental temperature results in the decrease in the life span, the content of unsaturated fatty acids and conjugated hydroxyperoxids; ketodienic content increases. Strong correlation was observed between the life span and the content of peroxidation products. As it is indicated by coefficients of bifactorial linear regression with interaction, conjugated hydroperoxids and ketodiens exert negative influence on the life span. Their combined effect on the life span is less significant than the sum of their separate effects, which indicates the existence of common "canals" of their influences on the life span.
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