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  • Title: Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis.
    Author: Oiwa H, Mihara K, Kan T, Tanaka M, Shindo H, Kumagai K, Sugiyama E.
    Journal: Intern Med; 2014; 53(16):1873-5. PubMed ID: 25130128.
    Abstract:
    Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.
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