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  • Title: [Clinical analysis of 4 Chinese hemophiliacs with human immunodeficiency virus infection].
    Author: Tang DJ, Xu YH, Dai D.
    Journal: Zhonghua Nei Ke Za Zhi; 1989 Aug; 28(8):466-8, 509. PubMed ID: 2513171.
    Abstract:
    Human immunodeficiency virus (HIV-is) now considered the causative agent of acquired immunodeficiency syndrome(AIDS). A high risk of AIDS has been reported among patients with hemophilia who received lyophilized commercial factor VIII and IX concentrates of American origin. In a prevalence survey conducted from September to December 1985, HIV antibodies were found in all the 4 patients with hemophilia treated with the batch number W87307, 955 I.U. of American commercial factor VIII concentrate supplied by Armour pharmaceutical Company U.S.A. One of the seropositive patients developed AIDS-related complex (ARC) and died of cerebral hemorrhage. The other three sero-positive patients had abnormalities in cell mediated immunity; among them two developed left lumbosacral radiculopathy and hemorrhagic herpes zoster and one remains well so far.
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