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  • Title: Pituitary response in the doubled GnRH-TRH test on the 5th day post partum or post abortum after ablactation by oral means of ethinylestradiol sulfonate.
    Author: Göretzlehner G, Wodrig W, Leminski A, Weber A, Ulrich U.
    Journal: Exp Clin Endocrinol; 1989 Sep; 94(1-2):177-86. PubMed ID: 2513213.
    Abstract:
    The function and reactivity of the hypothalamo - anterior pituitary axis had been tested after primary ablactation with ethinylestradiol sulfonate (EES) by means of the doubled GnRH-TRH-test. The reaction of the hypothalamo-pituitary axis is, in early puerperium, drastically reduced by GnRH stimulation. The physiological hyperprolactinemia of puerperium leads to a non-responsiveness by means of exogenous GnRH. Simultaneously there exists a greater sensitivity of the hypothalamo-pituitary system for the negative and a relatively lesser sensitivity for the positive feedback of estrogens in puerperium.
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