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  • Title: Structure and transfer of the vanA cluster in vanA-positive, vancomycin-susceptible Enterococcus faecium, and its revertant mutant.
    Author: Jung YH, Lee YS, Lee SY, Yoo JS, Yoo JI, Kim HS, Kim O, Yu JY.
    Journal: Diagn Microbiol Infect Dis; 2014 Oct; 80(2):148-50. PubMed ID: 25139845.
    Abstract:
    Of 18 vanA-positive vancomycin-susceptible Enterococcus faecium isolates, vanRS in the vanA cluster was detected in all isolates, while vanHAX was detected in only 2 isolates. Following exposure to glycopeptides, 22.2% of vancomycin-susceptible E. faecium (VSE) converted into vancomycin-resistant E. faecium. The vanA cluster of the revertant mutant was transferred to the VSE isolates.
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