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  • Title: Structure and hypolipidaemic activity of fucoidan extracted from brown seaweed Sargassum henslowianum.
    Author: Cuong HD, Thuy TT, Huong TT, Ly BM, Van TT.
    Journal: Nat Prod Res; 2015; 29(5):411-5. PubMed ID: 25141794.
    Abstract:
    The aim of this study is to elucidate the structure and investigate the hypolipidaemic activity of a fucoidan extracted from brown seaweed Sargassum henslowianum collected at Hai Van-Son Cha peninsula, Hue province, Vietnam by using tandem electrospray ionisation mass spectrometry. The results demonstrated that the fucoidan has α(1 → 3)-linked L-fucopyranose backbone and sulphate groups occupied mostly at C-2, C-4 and sometimes at C-3 position of fucose residues. The results of in vivo bioactivity examination revealed that the fucoidan in the dose of 100 mg/kgP/day by oral administration helped decrease cholesterol, triglyceride and LDL-cholesterol levels on obese mice.
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