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  • Title: Surface-enhanced Raman spectroscopy for simultaneous sensitive detection of multiple microRNAs in lung cancer cells.
    Author: Ye LP, Hu J, Liang L, Zhang CY.
    Journal: Chem Commun (Camb); 2014 Oct 14; 50(80):11883-6. PubMed ID: 25154520.
    Abstract:
    We develop circular exponential amplification reaction (EXPAR)-based surface-enhanced Raman spectroscopy (SERS) for simultaneous sensitive detection of multiple microRNAs in non-small cell lung cancer cells. This method possesses distinct advantages of excellent selectivity and high sensitivity with a detection limit of as low as 0.5 fM, which has improved by as much as 6 orders of magnitude as compared with the previously reported SERS-based direct assay.
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