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  • Title: Somatosensory investigation of patients with orofacial pain compared with controls.
    Author: de Siqueira SR, Teixeira MJ, de Siqueira JT.
    Journal: J Neuropsychiatry Clin Neurosci; 2014; 26(4):376-81. PubMed ID: 25162286.
    Abstract:
    The objective of this study was to investigate the sensorial characteristics of orofacial pain in patients compared with control subjects. A total of 336 subjects (282 patients and 54 control subjects) were evaluated to identify their thermal (cold and warm), tactile, and pain thresholds. Numbness was reported by 61.7% of the patients (p<0.001). Patients with trigeminal postherpetic neuralgia and burning mouth syndrome showed loss of thermal perception; patients with postherpetic neuralgia, burning mouth syndrome, and posttraumatic painful neuropathy had a decrease in tactile perception compared with the control subjects (p<0.001). In conclusion, other sensorial modalities besides pain are affected by neuropathic orofacial pain; these findings can help in the understanding of the pathophysiological mechanisms in orofacial pain.
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