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  • Title: Ten families of ankylosing spondylitis.
    Author: Fu X, Wang JC, Jia YM, Kang Q, An JB.
    Journal: Chin Med J (Engl); 1989 Sep; 102(9):709-12. PubMed ID: 2517085.
    Abstract:
    Twenty-two patients with ankylosing spondylitis (AS) from 10 families were studied with special attention to their clinical findings, HLA-B27 examinations and family histories. Results showed that HLA-B27 was positive in 19 and negative in 3. The hereditary relationship between ankylosing spondylitis and HLA-B27 in Chinese was similar to that in westerners. We consider that subjective symptoms and clinical findings are essential to early diagnosis of AS, but HLA-B27 examination and family history are supportive.
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