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  • Title: Synchronous posttransplant lymphoproliferative disorder and inflammatory myofibroblastic tumor of the lung in a 2-year-old liver transplanted boy: a case report.
    Author: Tepeoğlu M, Atılgan AO, Ozdemir BH, Haberal M.
    Journal: Exp Clin Transplant; 2015 Feb; 13(1):92-5. PubMed ID: 25184247.
    Abstract:
    Inflammatory myofibroblastic tumor is a rare benign lesion found mostly in children and young adults. It originates from the lung, abdominopelvic region, and retroperitoneum. The tumor is composed of myofibroblasts and inflammatory cell infiltration in the tissue. The cause and pathogenesis of this tumor are not completely understood. Epstein-Barr virus has been held responsible in some reported cases of inflammatory myofibroblastic tumors. Another tumor (which is known to be related to the Epstein-Barr virus) is posttransplant lymphoproliferative disorder. We report the case of a 2-year-old boy who underwent a liver transplant at the age of 9 months (the donor was his mother) because of biliary atresia. At 11 months after transplant, we detected posttransplant lymphoproliferative disorder and inflammatory myofibroblastic tumor concurrently. This entity is presented to highlight possible Epstein-Barr virus involvement in inflammatory myofibroblastic tumor of lung.
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