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  • Title: [Host-pathogen interaction of Legionella pneumophila].
    Author: Nagai H.
    Journal: Nihon Saikingaku Zasshi; 2014; 69(3):503-11. PubMed ID: 25186641.
    Abstract:
    Legionella are gram-negative bacteria ubiquitously found in freshwater and soil environments. Once inhaled by humans, Legionella infection could result in a severe form of pneumonia known as Legionellosis. Legionella translocate ~300 effector proteins into host cells via the Dot/Icm type IV secretion system, which is central to Legionella pathogenesis. Here I describe a brief review on recent advances in research on the molecular basis of Legionella-eukaryotic-cell interaction.
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