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  • Title: Facile construction of three contiguous stereogenic centers via dynamic kinetic resolution in asymmetric transfer hydrogenation of quinolines.
    Author: Chen MW, Cai XF, Chen ZP, Shi L, Zhou YG.
    Journal: Chem Commun (Camb); 2014 Oct 25; 50(83):12526-9. PubMed ID: 25196398.
    Abstract:
    An efficient and facile route to chiral tetrahydroquinolines with three contiguous stereogenic centers via a dynamic kinetic resolution process has been successfully developed by using chiral phosphoric acid as catalyst and Hantzsch ester as the hydrogen source with up to 89% ee.
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