These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Immunohistological features of synovitis in ankylosing spondylitis: a comparison with rheumatoid arthritis.
    Author: Kidd BL, Moore K, Walters MT, Smith JL, Cawley MI.
    Journal: Ann Rheum Dis; 1989 Feb; 48(2):92-8. PubMed ID: 2522758.
    Abstract:
    The immunohistological features of the synovial membrane in ankylosing spondylitis, HLA-B27 associated oligoarthritis, and rheumatoid arthritis wer examined with particular reference to T lymphocyte subsets. T helper (CD4+) cells clearly outnumbered T suppressor/cytotoxic (CD8+) cells in rheumatoid arthritis, whereas both cell types were present in equal numbers in ankylosing spondylitis. A reduction of CD4+/CD45R+ suppressor/inducer cells relative to CD4+/UCHL1+ helper/inducer cells was apparent in all diagnostic groups. The observations were suggestive of disease specific inflammatory responses within synovial membrane.
    [Abstract] [Full Text] [Related] [New Search]