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  • Title: Structure elucidation and cytotoxic evaluation of new polyacetylenes from a marine sponge Petrosia sp.
    Author: Juan YS, Lee CC, Tsao CW, Lu MC, El-Shazly M, Shih HC, Chen YC, Wu YC, Su JH.
    Journal: Int J Mol Sci; 2014 Sep 18; 15(9):16511-21. PubMed ID: 25238415.
    Abstract:
    The sponge Petrosia sp. yielded five polyacetylenic compounds (1-5), including two new polyacetylenes, petrosianynes A (1) and B (2). The structures of these compounds were elucidated by detailed spectroscopic analysis and by comparison with the physical and spectral data of related known analogues. Compounds 1-5 exhibited significant cytotoxic activity against a limited panel of cancer cell lines.
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