These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Modulation of mesolimbic dopaminergic projections by beta-endorphin in the rat.
    Author: Iyengar S, Kim HS, Marien MR, McHugh D, Wood PL.
    Journal: Neuropharmacology; 1989 Feb; 28(2):123-8. PubMed ID: 2524013.
    Abstract:
    Intracerebroventricular injection of beta-endorphin stimulated the metabolism of dopamine in a dose-dependent, opiate antagonist-reversible manner. Local injections into the nucleus accumbens also caused similar increases, indicating that the actions of this peptide on mesolimbic dopaminergic projections were occurring at opioid receptor sites within the nucleus accumbens. Tolerance experiments suggested that epsilon opioid receptors may be involved in mediating these effects in the n. accumbens, unlike in the striatum.
    [Abstract] [Full Text] [Related] [New Search]