These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Simultaneous determination of norepinephrine, acetaminophen and tyrosine by differential pulse voltammetry using Au-nanoparticles/poly(2-amino-2-hydroxymethyl-propane-1,3-diol) film modified glassy carbon electrode.
    Author: Taei M, Ramazani G.
    Journal: Colloids Surf B Biointerfaces; 2014 Nov 01; 123():23-32. PubMed ID: 25240479.
    Abstract:
    A novel Au-nanoparticles/poly-(2-amino-2-hydroxymethyl-propane-1,3-diol) film modified glassy carbon electrode (AuNPs/poly(trisamine)/GCE) was constructed for the simultaneous determination of norepinephrine (NE), acetaminophen (AC) and L-tyrosine (Tyr) by differential pulse voltammetry. Electrochemical impedance spectroscopy and scanning electron microscopy indicate that the trisamine film was successfully polymerized on the surface of GCE and the film efficiently decreased the charge transfer resistance value of electrode and improved the electron transfer kinetic between analytes and electrode. The separation of the oxidation peak potentials for NE-AC and AC-Tyr were about 160 mV and 240 mV, respectively. The calibration curves for NE, AC and Tyr were obtained in the range of 1.3-230.1 μmol L(-1), 1.90-188.0 μmol L(-1), and 3.9-61.8 μmol L(-1), respectively. The detection limits (S/N=3) were 0.07 μmol L(-1), 0.1 μmol L(-1) and 0.9 μmol L(-1), for NE, AC and Tyr, respectively. The diffusion coefficient and the catalytic rate constant for the oxidation reaction of NE at AuNPs/poly(trisamine)/GCE were calculated as 1.55 (±0.2)×10(-6) cm2 s(-1) and 2.28 (±0.17)×10(3) mol(-1) L s(-1), respectively. Finally, AuNPs/poly(trisamine)/GCE was satisfactorily used for the determination of NE, AC, and Tyr in pharmaceutical and biological samples.
    [Abstract] [Full Text] [Related] [New Search]