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Title: Pentacam vs SP3000P specular microscopy in measuring corneal thickness.
Author: De Bernardo M, Borrelli M, Mariniello M, Lanza M, Rosa N.
Journal: Cont Lens Anterior Eye; 2015 Feb; 38(1):21-7. PubMed ID: 25240777.
Abstract:
PURPOSE: To compare corneal thickness (CT) measurements obtained with SP3000P specular microscope and Pentacam in eyes screened to undergo refractive surgery (RS). METHODS: In this prospective study, a non-randomized consecutive series of 73 healthy eyes (age range: 14-78 years; mean=38.4±14.9) underwent CT measurement with both Oculus Pentacam and Topcon SP3000P specular microscope to assess their suitability to undergo corneal RS. RESULTS: CT measurements with SP3000P ranged from 451 to 609 μs (mean 523.1±34.4 μs). The measurements obtained with Pentacam ranged at the corneal apex from 477 to 672 μs (mean 558.9±38.9 μs), at the pupil center from 477 to 672 μs (mean 557.9±38.9 μs) and at the thinnest point from 474 to 669 μs (mean 551.1±39.4 μs). CT measurements showed a good correlation but a statistically significant difference at the pupil center (mean -34.9±14.6 μs, R(2)=0.860, p<0.001), at the apex (mean -35.9±14.9 μs, R(2)=0.856, p<0.001) and at the thinnest point (mean -32±14.8 μs, R(2)=0.862, p<0.001). The calculated regression formulas were: y=0.816x+66.94 for the apex, y=0.819x+66.07 for the pupil center and y=0.810x+73.13 for the thinnest point; where y is the CT measured with the SP3000P and x is the measurement obtained with the Oculus Pentacam. CONCLUSIONS: Our results suggest that SP3000P measures thinner corneas compared to the Pentacam and that the correcting factor we identified should be applied to make comparisons between these two devices.

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