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  • Title: Primary Epstein-Barr virus infection and probable parvovirus B19 reactivation resulting in fulminant hepatitis and fulfilling five of eight criteria for hemophagocytic lymphohistiocytosis.
    Author: Karrasch M, Felber J, Keller PM, Kletta C, Egerer R, Bohnert J, Hermann B, Pfister W, Theis B, Petersen I, Stallmach A, Baier M.
    Journal: Int J Infect Dis; 2014 Nov; 28():143-6. PubMed ID: 25242697.
    Abstract:
    A case of primary Epstein-Barr virus (EBV) infection/parvovirus B19 reactivation fulfilling five of eight criteria for hemophagocytic lymphohistiocytosis (HLH) is presented. Despite two coinciding viral infections, massive splenomegaly, and fulminant hepatitis, the patient had a good clinical outcome, probably due to an early onset form of HLH with normal leukocyte count, normal natural killer (NK) cell function, and a lack of hemophagocytosis.
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