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  • Title: [A new eremophilane derivative from Ligularia intermedia].
    Author: Li SL, Liu YH, Hao QJ, Zhang XM, Jia YM, Li N.
    Journal: Zhongguo Zhong Yao Za Zhi; 2014 Jun; 39(12):2281-3. PubMed ID: 25244759.
    Abstract:
    A new eremophilane derivative, (3aR,4R,5S,7S,7aS)-2-acetyl-7,7a-dihydroxy-3a,4-dimethyl-3a,4,5,6,7,7a-hexahydro-3H-inden-5-yl acetate (1) and three known compounds, 10beta-hydroxy-eremophil-7 (11)-en-12,8alpha-olide(2), beta-sitosterol (3) and beta-daucosterol(4) have been isolated from Ligularia intermedia. The compounds were isolated by column chromatography on silica gel and Sephadex LH-20,and identified on the basis of spectral analyses (MS, 1H-NMR, 13C-NMR).
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