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  • Title: Brønsted acid accelerated Pd-catalyzed direct asymmetric allylic alkylation of azlactones with simple allylic alcohols: a practical access to quaternary allylic amino acid derivatives.
    Author: Zhou H, Yang H, Liu M, Xia C, Jiang G.
    Journal: Org Lett; 2014 Oct 17; 16(20):5350-3. PubMed ID: 25265423.
    Abstract:
    A Brønsted acid accelerated Pd-catalyzed asymmetric allylic alkylation of azlactones with simple allylic alcohols under mild reaction conditions has been realized, which provides a direct and readily scalable approach for the synthesis of all-carbon quaternary allylic amino acid derivatives in excellent yields and good enantioselectivities.
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