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  • Title: [Combination with medroxyprogesterone acetate and chemotherapy making possible complete removal of uterine corpus carcinoma].
    Author: Tajima H, Okada T, Fujimori Y, Tomioka Y, Hirano M, Yoshida T, Ikeda S, Hata T.
    Journal: Gan To Kagaku Ryoho; 1989 Jul; 16(7):2461-4. PubMed ID: 2526620.
    Abstract:
    A case of uterine corpus carcinoma (stage III) after surgical resection of her primary lesion was treated with a medroxyprogesterone acetate (MPA) and PAE (CDDP, adriamycin and etoposide) regimen. The patient has been given MPA during a three-month period and received four courses of PAE regimen. The residual tumor was decreased and removed completely at the second-look operation. Pathologically, the carcinoma cells were clearly changed in loss of atrophy or degeneration by MPA or PAE regimen. After the second-look operation, the patient underwent 4 courses of PAE regimen and was given MPA continuously. We have not recognized any recurrence of carcinoma for seven months after the second look operation.
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