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Title: The Oxeatamides: nitrogenous spongian diterpenes from the New Zealand marine sponge Darwinella oxeata. Author: Wojnar JM, Dowle KO, Northcote PT. Journal: J Nat Prod; 2014 Oct 24; 77(10):2288-95. PubMed ID: 25272326. Abstract: As part of our ongoing search for novel and bioactive compounds from New Zealand marine organisms, we investigated the extracts of the sponge Darwinella oxeata. NMR-guided fractionation led to the isolation of nine new nitrogenous spongian diterpenes, oxeatamide A (1), iso-oxeatamide A (2), oxeatamides B-G (3-8), and oxeatamide A 23-methyl ester (9), as well as two known compounds, membranolides C and D (10, 11).[Abstract] [Full Text] [Related] [New Search]