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  • Title: Effects in vivo and in vitro of benthiocarb on developing rat (Wistar strain) brain Mg2+ and Ca2+-ATPases.
    Author: Srinivas PN, Reddy GR, Chetty CS.
    Journal: Biochem Int; 1989 Jul; 19(1):145-53. PubMed ID: 2528350.
    Abstract:
    Effects in vivo and in vitro of benthiocarb on developing rat brain Mg2+ and Ca2+-ATPases have been studied. Decreased activities of Mg2+ and Ca2+-ATPases suggests impairment in energy synthesis and utilization processes in developing CNS of rat during benthiocarb poisoning. Effects in vitro of benthiocarb on these enzymes revealed that Km (Michaelis-Menten Constant) of both the enzymes increased whereas Vmax (Maximal velocity) decreased significantly indicating mixed type of inhibition on these enzymes by benthiocarb.
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