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Title: Innate immune sensing of nucleic acids from mycobacteria. Author: Yamashiro LH, Oliveira SC, Báfica A. Journal: Microbes Infect; 2014 Dec; 16(12):991-7. PubMed ID: 25284681. Abstract: Endosomal and cytosolic receptors engage recognition of mycobacterial-derived nucleic acids (MyNAs). In contrast, virulent mycobacteria may utilize nucleic acid recognition pathways to escape the host immune system. This short review will summarize the mechanisms by which MyNAs are sensed and how they influence host protective responses.[Abstract] [Full Text] [Related] [New Search]