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  • Title: [Clinical functional study of a new delayed-action preparation of "once a day" anhydrous theophylline in patients with chronic obstructive bronchopneumopathy].
    Author: Gatto PG, Bruzzoni A, Valenti V.
    Journal: Clin Ter; 1989 Jul 15; 130(1):45-9. PubMed ID: 2529079.
    Abstract:
    A new long-acting theophylline formulation for once-daily administration has been tried in twenty patients with flare-ups of chronic obstructive bronchopulmonary disease (COPD). Clinical results were good and untoward side effects were not observed. Theophylline blood level was tested on the first day and once steady state had been achieved, and was always within the therapeutic range.
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