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  • Title: The effects of ipratropium bromide and fenoterol nebulizer solutions in children with asthma.
    Author: Freeman J, Landau LI.
    Journal: Clin Pediatr (Phila); 1989 Dec; 28(12):556-60. PubMed ID: 2531051.
    Abstract:
    The effects of nebulized solutions of ipratropium bromide and fenoterol combined were compared with the response to either preparation alone in single dose and longer-term administration in children who had asthma. The combination produced a slightly greater response than either alone, especially in peak expiratory flow. Over a 1-month period, there were no significant differences in symptom scores or lung function parameters between the combination of ipratropium bromide and fenoterol and fenoterol alone in a group of children who had asthma. It is possible that the addition of ipratropium bromide to a sympathomimetic drug may be useful in a subgroup of asthmatics, particularly if there is a considerable large airway contribution to bronchial narrowing.
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