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  • Title: Acid phosphatase (EC 3.1.3.2) synthesis by phosphorus regulatory mutant strains of Neurospora crassa.
    Author: Han SW, Rossi A.
    Journal: Braz J Med Biol Res; 1989; 22(4):423-31. PubMed ID: 2531620.
    Abstract:
    1. Even though altered forms of acid phosphatase II were synthesized by the mutant strains nuc-1A and nuc-2A of N. crassa, their synthesis was independent of exogenous phosphate concentrations. 2. Synthesis of acid phosphatase I by nuc-2A was also insensitive to exogenous phosphate concentrations. When nuc-1A was grown on a low-phosphate medium, it also produced a heat-labile acid phosphatase in addition to a I-like acid phosphatase. I-like acid phosphatase was not detected in the mycelium of the pregc mutant strain grown on low-phosphate medium. 3. These results are consistent with the participation of the nuc-2, preg and nuc-1 genes in regulating the transport and/or secretion of acid phosphatase and probably other phosphatases by Neurospora crassa.
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