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  • Title: Epstein-Barr virus-associated smooth muscle tumors in AIDS patients: a largest case (series).
    Author: Issarachaikul R, Shuangshoti S, Suankratay C.
    Journal: Intern Med; 2014; 53(20):2391-6. PubMed ID: 25318810.
    Abstract:
    This study aimed to determine the outcomes of Epstein-Barr virus (EBV)-associated smooth muscle tumors (SMTs) in AIDS patients at King Chulalongkorn Memorial Hospital, Bangkok, Thailand, treated from 2001-2011. Of the 17 patients, there were five men with a median CD4 count of 26 cells/μL. Eight and nine patients had single and multiple sites, respectively. The most common site was the cranial epidura (58.8%). All patients had EBV within the tumor. Seven patients underwent surgery. The median follow-up was one year. The mortality rate was 41.2%. All patients with undetectable HIV viremia survived. This is the largest case series regarding EBV-associated SMTs in AIDS patients with a long follow-up period.
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