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  • Title: Orthostatic hypertension in children and adolescents with postural tachycardia syndrome.
    Author: Zhang Q, Li J, Xie Y, Zhao J, Du J.
    Journal: J Trop Pediatr; 2014 Dec; 60(6):461-6. PubMed ID: 25326283.
    Abstract:
    OBJECTIVE: We described a heterogenous group of children disabled by postural tachycardia syndrome (POTS) and evident orthostatic hypertension (OHT). METHODS: Twenty patients met the diagnostic criteria for POTS + OHT. Their clinical characteristics were compared with those in 76 patients with POTS alone and 20 healthy age-matched controls. Multivariate logistic regression analysis was used to identify independent risk factors for POTS + OHT. RESULTS: Supine systolic blood pressure (SBP) was lower in the POTS + OHT group than in the POTS group (p < 0.05). Compared with the POTS group, the POTS + OHT group showed markedly increased upright SBP, upright heart rate (HR) and HR changes (p < 0.05). Headache was more common in the POTS + OHT group than in the POTS group (p < 0.05). Logistic regression analysis revealed that low supine SBP and headache were independent risk factors for OHT in POTS patients. CONCLUSIONS: Headache and low supine SBP were the main clinical characteristics of a novel syndrome of POTS associated with OHT.
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