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  • Title: [Clinical signification of localization of S protein and late components in the skin from lupus patients].
    Author: Ogawa M, Hirakawa T, Saida Y, Fujisawa R, Ito S, Sugisaki T.
    Journal: Nihon Hifuka Gakkai Zasshi; 1989 Apr; 99(4):435-41. PubMed ID: 2533285.
    Abstract:
    We studied frozen tissue of lesional skin and normal-appearing skin from SLE patients and DLE patients by immunofluorescence. S-protein and late components (C5, C7, C9) were localized at the dermal-epidermal junction of the lesional skin from SLE and DLE patients. All specimens of normal-appearing skin from patients with SLE were free of deposits of S-protein and late components. These results suggest that late components may play a role in the development of skin lesions of SLE and DLE.
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