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  • Title: [The role of atrial natriuretic peptide in the pathogenesis of arterial hypertension in chronic glomerulonephritis].
    Author: Konstantinov IuV, Tsanava KA, Shulutko BI.
    Journal: Klin Med (Mosk); 1989 Oct; 67(10):57-60. PubMed ID: 2533305.
    Abstract:
    Radioimmunoassay was used in 39 patients with chronic glomerulonephritis and secondary hypertension to measure atrial natriuretic peptide concentration in blood plasma. The latter concentration appeared unrelated to the patients' age, duration and gravity of hypertension, the degree of renal insufficiency, hyperhydration and activation of renin-angiotensin-aldosterone++ system. The conclusion is made on minor contribution of this short-acting peptide to pathogenesis of arterial hypertension in chronic glomerulonephritis.
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