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  • Title: [Testing of a hyperimmune serum in calves infected intranasally with Mycoplasma bovis].
    Author: Brys A, Pfützner H.
    Journal: Arch Exp Veterinarmed; 1989; 43(5):677-83. PubMed ID: 2533483.
    Abstract:
    Mycoplasma (M.) bovis hyperimmune serum was subcutaneously injected to 16 of 26 calves repeatedly intranasally infected with M. bovis, during and/or after experimental infection. Antibody titres between 1:32 and 1:256 were recorded by means of indirect haemagglutination from the calves treated. Transmission of film-inhibitory antibodies failed to work. Neither clinical manifestations nor pathologico-anatomic alterations to the lungs of experimentally infected animals were mitigated by hyperimmune serum treatment. M. bovis, in high germ counts, was re-isolated from nasal swabs, trachea, pulmonary lymph nodes, and inflammatory lung tissue of both treated and untreated calves.
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