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  • Title: Terpenoids from the root bark of Pterolobium macropterum.
    Author: Suthiwong J, Pitchuanchom S, Wattanawongdon W, Hahnvajanawong C, Yenjai C.
    Journal: J Nat Prod; 2014 Nov 26; 77(11):2432-7. PubMed ID: 25337628.
    Abstract:
    Five new compounds, including pteroloterins A-C (1, 3, and 4), 1β-acetoxytaepeenin C (2), and 8aα-hydroxycadinenal (5), and 11 known compounds were isolated from the root bark of Pterolobium macropterum. All compounds were evaluated for cytotoxicity against the cholangiocarcinoma cell lines. Compound 9 showed weak cytotoxicity against the KKU-M139 cell line with an IC50 value of 23.24 ± 0.18 μM and showed no activity against normal cells.
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